SLU-PP-322 5 mg

SLU-PP-322 5 mg — the exercise-mimetic ERR agonist
A small molecule that activates the transcriptional machinery normally switched on by physical exertion. SLU-PP-322 is among the most talked-about compounds in current metabolic research.

What is SLU-PP-322?

SLU-PP-322 is a synthetic pan-agonist of the estrogen-related receptors, a family of orphan nuclear receptors (ERR-alpha, ERR-beta and ERR-gamma) that govern the transcriptional programmes controlling mitochondrial biogenesis and oxidative metabolism. Its research designation as an exercise mimetic reflects the observation that ERR activation drives many of the same gene-expression signatures produced by endurance activity. Rather than acting on a cell-surface receptor, it operates at the Level of nuclear transcription — a fundamentally different mechanism from the peptide secretagogues it is often shelved alongside.

Research interest

• ERR nuclear receptor pharmacology — studied as a pan-agonist tool compound across the ERR-alpha, beta and gamma subtypes.
• Mitochondrial biogenesis — investigated in research contexts examining transcriptional control of mitochondrial density and oxidative capacity.
• Exercise-mimetic biology — of interest to researchers exploring pharmacological reproduction of endurance-training gene signatures.
• Energy expenditure — referenced in preclinical literature concerned with fatty acid oxidation and substrate preference.
• Skeletal muscle transcriptomics — used in studies mapping downstream gene-expression changes following nuclear receptor activation.

Because SLU-PP-322 is a small molecule rather than a peptide, its handling profile differs: solubility characteristics and solvent compatibility become the primary practical considerations, and laboratories should establish these against their own validated procedures before use.

Specifications

• Content: 5 mg of active compound per vial
• Form: Lyophilised powder / solid compound (vial)
• Purity: Pharmaceutical-grade, batch-tested and lot-traceable
• Presentation: Sealed, tamper-evident single vial
• Storage: -20 °C sealed, kept dry and dark

Handling & storage

Lyophilised material is best held at -20 °C in the sealed, unopened vial. Refrigeration at 2-8 °C is acceptable for short-term handling. Protect from light, humidity and repeated freeze-thaw exposure. Keep the vial sealed, dry and frozen, protected from light. Allow it to warm fully to room temperature before opening so that no moisture condenses onto the compound. Solvent selection and stock preparation should follow the laboratory's own validated protocol; prepared stocks are typically aliquoted, frozen and protected from repeated thaw cycles.

Why source it here

• Purity you can document — batch-tested material with traceable lot identification.
• Direct European supply — authentic, sealed vials handled to a strict cold-chain-aware standard.
• No compromise on consistency — controlled sourcing keeps material comparable between orders.
• Rapid discreet dispatch — tracked EU shipping in plain packaging.

For research purposes only. Not a medicinal product. Not for human or veterinary consumption. Intended for qualified laboratory research use only. No statement on this page is a medical claim, and no administration, dosing or protocol guidance is offered or implied.

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