GHRP-2 10 mg

GHRP-2 10 mg — a benchmark growth hormone secretagogue for endocrine research.
GHRP-2 is one of the most widely referenced synthetic growth hormone-releasing Peptides in the laboratory literature. Researchers turn to it when they need a well-characterised, reproducible tool for probing the somatotropic axis. Supplied as a lyophilised 10 mg vial, batch-tested and sealed for laboratory use.

What is GHRP-2?

GHRP-2 (growth hormone-releasing peptide 2, also catalogued as pralmorelin) is a short synthetic hexapeptide belonging to the growth hormone secretagogue class. Unlike GHRH analogues, which act at the GHRH receptor, secretagogues of this family are studied for their interaction with the growth hormone secretagogue receptor — the same receptor population engaged by the endogenous peptide ghrelin. Its compact sequence, synthetic stability and strong characterisation in the published record make it a common reference compound when investigators need a positive control or a comparator against newer secretagogue candidates.

Research interest

• Somatotropic axis signalling — investigated in models examining how pulsatile growth hormone release is initiated and regulated at the pituitary Level.
• GHS-R pharmacology — used in receptor-binding and receptor-occupancy work exploring the ghrelin receptor system.
• Comparative secretagogue studies — frequently employed as a reference peptide alongside GHRP-6, hexarelin and GHRH analogues.
• Endocrine feedback research — of interest to researchers examining interactions between secretagogue signalling and downstream hormonal mediators.
• Assay development — applied in the validation of immunoassays and analytical methods targeting peptide secretagogues.

Specifications

• Content: 10 mg of active substance per vial
• Form: Lyophilised powder (sealed vial)
• Purity: Pharmaceutical-grade, batch-tested
• Storage: Sealed and lyophilised at 2–8 °C; long-term at −20 °C, protected from light and moisture

Handling & storage

Short peptides of this class are hygroscopic and degrade fastest when moisture, heat and light are allowed to reach the cake. Keep the vial sealed and refrigerated on arrival, and allow it to equilibrate to room temperature before the stopper is broken so that condensation does not form on the powder. Reconstitution in the laboratory should follow the receiving facility's own validated protocol; solvent should be introduced gently down the vial wall rather than directly onto the cake, and the vial swirled rather than shaken to avoid shear-induced aggregation. Reconstituted material is markedly less stable than the dry form and should be held cold, protected from light and used within the working window established by the laboratory. Avoid repeated freeze–thaw cycling; aliquot instead.

GHRP-2 10 mg in depth: history, research findings and alternatives

The growth hormone-releasing peptides grew out of work by Cyril Bowers and Frank Momany, who described GHRP-6 in 1984. GHRP-2 followed in the early 1990s as a more potent analogue, built partly from D-amino acids that make it more resistant to enzymatic breakdown. Remarkably, both were designed before anyone knew which receptor they acted on: the growth hormone secretagogue receptor was cloned in 1996, and its natural ligand, ghrelin, was only identified in 1999. In Japan, pralmorelin is used as a diagnostic agent when testing adults for growth hormone deficiency; in the EU it is not an authorised medicine.

Human studies describe a strong but short-lived GH pulse, accompanied by modest, transient rises in cortisol and prolactin and by increased hunger. The size of the response depends on the pituitary's own reserve and on somatostatin tone, so it varies widely between subjects, and continuous exposure has been reported to blunt it. Because raised GH and IGF-1 affect glucose metabolism, clinical studies monitor IGF-1, blood glucose and cortisol; any health question about GH-axis compounds belongs with a doctor.

Frequently asked questions

Where can I buy GHRP-2 online in Europe?

You can order GHRP-2 online from Rogue and have it delivered anywhere in the EU, from Ireland and France to Finland and the Netherlands. Orders ship from EU stock, are tracked and arrive in plain, discreet packaging, and you can pay by SEPA bank transfer or through a secure card payment link. Rogue's peptides are sold for research purposes only and are not for human consumption.

How much does GHRP-2 cost?

The current price of the 10 mg vial is shown at the top of this page. When you order three or more vials, multi-buy discounts are applied automatically, and the full price ladder is displayed on the page. Orders over €30 ship free. Be cautious with offers far below the usual market price: they can hide untraceable material.

How can I tell original GHRP-2 from a fake?

A genuine vial arrives sealed with an intact cap, a label showing the batch number and expiry date, and a dry white cake or powder inside. The batch certificate should report HPLC purity and a mass-spectrometry identity check that matches GHRP-2's molecular mass of roughly 818 Da. Be wary of unlabelled powders, missing batch numbers or certificates that cannot be matched to the vial in your hand.

Is GHRP-2 a powder, or is there an oral form?

Rogue supplies GHRP-2 as a lyophilised (freeze-dried) powder in a sealed 10 mg vial; it is not sold as tablets or capsules. Early research did look at oral administration, but peptides like this are largely broken down in the digestive tract and oral bioavailability was reported to be low. Some suppliers sell 5 mg vials: the compound is identical, only the quantity per vial differs.

Can I get GHRP-2 from a pharmacy or on prescription?

No. GHRP-2 is a research compound rather than an approved medicine, so it is not dispensed by pharmacies or available on prescription. Rules on buying and holding research peptides differ from one country to the next, so check the regulations where you live before you order.

Is GHRP-2 banned in sport?

Yes. Growth hormone-releasing peptides, GHRP-2 (pralmorelin) among them, are named on the World Anti-Doping Agency's Prohibited List, and anti-doping laboratories have validated methods for detecting GHRPs and their metabolites in urine. Athletes who are subject to testing should treat it as prohibited at all times.

Why source from Rogue

• Verified purity — every batch is traceable, analytically tested and released against its own certificate.
• European supply chain — sealed, authentic vials, shipped from within the EU and never sourced grey-market.
• Discreet, tracked delivery — fast dispatch across Europe in protective packaging, tracked end to end.

For research purposes only. Not a medicinal product. Not for human or veterinary consumption. Intended for qualified laboratory research use only.