Cagrilintide + Semaglutide 5 mg + 5 mg

Cagrilintide + Semaglutide 5 mg + 5 mg — two satiety pathways in a single research vial.
Dual-pathway metabolic research has become one of the most active areas in the field, and this co-formulated vial puts both principal candidates in one place: a long-acting amylin analogue alongside a long-acting GLP-1 receptor agonist. Supplied as a lyophilised 5 mg + 5 mg vial.

What is Cagrilintide + Semaglutide?

This is a combination research preparation containing two distinct engineered Peptides. Cagrilintide is a lipidated, aggregation-resistant analogue of amylin, the pancreatic hormone co-secreted with insulin, and is studied at amylin and calcitonin receptor populations. Semaglutide is a stabilised GLP-1 analogue with substitutions and a fatty-diacid chain that resist enzymatic cleavage and promote albumin binding. Their interest as a pair comes from mechanistic non-overlap: amylin and incretin signalling converge on energy balance through different receptor systems and different anatomical relays, which makes the combination a natural subject for additive- and synergy-focused investigation.

Research interest

• Dual-pathway satiety signalling — investigated in models examining whether amylin and GLP-1 inputs act additively on energy intake.
• Comparative receptor pharmacology — used to separate the contributions of AMY and GLP-1 receptor populations.
• Energy balance research — of interest to researchers examining substrate handling and body composition in preclinical models.
• Combination formulation chemistry — a case study in co-formulating two lipidated peptides with differing stability profiles.
• Gastrointestinal signalling — studied in work on gut–brain axis mediators of meal termination.

Specifications

• Content: 5 mg cagrilintide + 5 mg semaglutide of active substances per vial
• Form: Lyophilised powder (sealed vial)
• Purity: Pharmaceutical-grade, batch-tested
• Storage: Sealed at 2–8 °C; −20 °C for long-term holding, dry and protected from light

Handling & storage

Because two lipidated peptides share a single cake, both must be brought into solution cleanly and simultaneously — incomplete or uneven dissolution undermines any comparative work built on the vial. Keep it sealed, cold and dry, and equilibrate to room temperature before opening. Reconstitute under your laboratory's validated protocol, running solvent gently down the vial wall; never shake or vortex, since foaming and shear promote aggregation in amylin-family sequences in particular. Confirm a clear, particulate-free solution before proceeding. Hold reconstituted material refrigerated and dark, aliquot into low-binding single-use tubes, and avoid repeated freeze–thaw cycling.

Why source from Rogue

• Verified purity — batch-tested material with documented identity and assay results.
• European supply chain — factory-sealed vials held in controlled conditions, never repackaged or grey-market.
• Discreet, tracked delivery — rapid EU-wide dispatch in unbranded, protective outer packaging.

For research purposes only. Not a medicinal product. Not for human or veterinary consumption. Intended for qualified laboratory research use only.