Cagrilintide 5 mg

Cagrilintide 5 mg — a long-acting amylin analogue for metabolic research.
Cagrilintide represents one of the more significant recent additions to the metabolic peptide toolkit: a co-engineered amylin and calcitonin receptor agonist designed for extended stability. Laboratories studying satiety signalling now treat it as a standard comparator alongside incretin-pathway compounds. Supplied as a 5 mg lyophilised vial.

What is Cagrilintide?

Cagrilintide is a synthetic long-acting analogue of human amylin, the pancreatic hormone co-secreted with insulin from beta cells. Native amylin is notoriously difficult to work with because it aggregates readily into amyloid fibrils; cagrilintide's sequence is engineered specifically to resist that aggregation while retaining activity across the amylin and calcitonin receptor family. It is lipidated to extend its circulating half-life, which is why it appears in research contexts as a durable-exposure tool rather than a transient probe. Its position is distinct from GLP-1 analogues — it addresses a parallel satiety pathway, which is precisely why combination research has become so active.

Research interest

• Satiety signalling — investigated in models examining amylin-mediated control of meal termination and energy intake.
• Amylin receptor pharmacology — used to probe AMY receptor subtypes and calcitonin receptor crosstalk.
• Body composition research — of interest to researchers examining energy balance in preclinical metabolic models.
• Combination pathway studies — frequently paired with incretin analogues to examine additive satiety mechanisms.
• Peptide aggregation chemistry — a worked case study in engineering amyloid resistance into a native sequence.

Specifications

• Content: 5 mg of active substance per vial
• Form: Lyophilised powder (sealed vial)
• Purity: Pharmaceutical-grade, batch-tested
• Storage: 2–8 °C sealed; −20 °C for long-term, dry and protected from light

Handling & storage

Amylin-family Peptides are the classic example of aggregation-prone material, and even engineered analogues reward careful technique. Keep the vial sealed, cold and dry, and equilibrate it to room temperature before opening. When reconstituting under your laboratory's validated protocol, add solvent gently down the vial wall and let the cake dissolve without agitation — shaking, vortexing and foaming all promote nucleation and fibril formation. Inspect the solution: it should be clear and free of visible particulates or wisps. Hold reconstituted material refrigerated, protected from light, in low-binding aliquots for single use, and avoid repeated freeze–thaw cycles entirely.

Why source from Rogue

• Verified purity — batch-tested material with documented identity and assay results.
• European supply chain — factory-sealed vials held in controlled conditions, never repackaged or grey-market.
• Discreet, tracked delivery — rapid EU-wide dispatch in unbranded, protective outer packaging.

For research purposes only. Not a medicinal product. Not for human or veterinary consumption. Intended for qualified laboratory research use only.

Related: Melatonin 10 mg · HMG 75 IU