Alprostadil 20 mcg

Alprostadil 20 mcg — a prostaglandin reference standard for vascular research.
Alprostadil is the synthetic form of prostaglandin E1, one of the most thoroughly characterised vasoactive lipid mediators in the literature. For laboratories working on vascular tone, it functions as a precise, well-documented positive control. Supplied as a 20 mcg lyophilised vial.

What is Alprostadil?

Alprostadil is synthetic prostaglandin E1 (PGE1), a member of the eicosanoid family of lipid signalling molecules derived from arachidonic acid. Unlike the amino-acid Peptides in this category, it is a small lipid mediator, and it is studied for its interaction with EP-family prostaglandin receptors and the downstream cyclic AMP signalling that follows. PGE1 is a canonical vasodilator in the research record and a standard reference compound in smooth muscle and platelet studies. The very low fill mass — micrograms rather than milligrams — reflects the potency profile documented across that literature.

Research interest

• Vasodilation mechanisms — a reference agonist in vascular smooth muscle relaxation assays.
• Prostaglandin receptor pharmacology — used to characterise EP receptor subtypes and cAMP coupling.
• Microcirculation research — investigated in models examining peripheral blood flow regulation.
• Platelet biology — of interest to researchers examining aggregation signalling pathways.
• Eicosanoid analytical work — applied as a standard in chromatographic and mass-spectrometric method development.

Specifications

• Content: 20 mcg of active substance per vial
• Form: Lyophilised powder (sealed vial)
• Purity: Pharmaceutical-grade, batch-tested
• Storage: Refrigerated at 2–8 °C sealed; −20 °C for long-term, dry and strictly protected from light

Handling & storage

At a 20 mcg fill, quantitative recovery is the dominant handling concern — the visible cake is minimal and adsorptive losses are proportionally large. Equilibrate the sealed vial to room temperature before opening, then reconstitute under your validated protocol using solvent directed down the vial wall so the full inner surface is rinsed. Prostaglandins are considerably less stable than peptides at ambient temperature and are sensitive to light, heat and oxidation, so work promptly, keep containers amber or foil-wrapped, and return material to cold storage without delay. Prepare single-use aliquots in low-binding vessels, avoid freeze–thaw cycling, and prepare working dilutions fresh on the day of use.

Why source from Rogue

• Verified purity — every batch is traceable, analytically tested and released against its own certificate.
• European supply chain — sealed, authentic vials, shipped from within the EU and never sourced grey-market.
• Discreet, tracked delivery — fast dispatch across Europe in protective packaging, tracked end to end.

For research purposes only. Not a medicinal product. Not for human or veterinary consumption. Intended for qualified laboratory research use only.

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